YES on Prop 38

Immunology Medical Research & Cures Initiative

Proposition 38 on the November 2026 ballot will fund breakthrough immunology medical research to cure and prevent devastating diseases that impact millions of Californians, including cancer, heart disease, and Alzheimer's.

Key reasons to vote YES on Prop 38, the Immunology Medical Research & Cures Initiative:

Provides critical funding for immunology research

Dedicated funding for cancer, Alzheimer's and heart disease research

Fosters collaboration between leading scientists and physicians

Mandates strong accountability and transparency

Designed to pay for itself – including interest

Requires 20% discount on treatments and cures for Californians

Our Coalition

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*Partial list View All Supporters

What are Immunology and Immunotherapies?

Immunology is the field of medical science focused on understanding the immune system and its role in preventing and treating diseases. By supporting immunology research and the development of innovative immunotherapies for diseases like cancer, Alzheimer's, Parkinson's and heart disease, Prop 38 could save your life and the life of someone you love.

Learn about Cures in our Lifetime

What Our Supporters Are Saying

  • "Immunotherapy saved my life — I was just weeks away from losing my life when a breakthrough treatment gave me a second chance. That’s why I’m proud to support Prop 38, because no one should be told hope is out of reach when we have the science to save them."

    Laurie Adami
    Laurie Adami
    Cancer Pioneer and Patient Advocate
  • "Having spent decades at the forefront of disease prevention, I understand the promise of vaccines, therapies and cures that come from immunology research. Prop 38 is a vital step toward decoding the human immune system and accelerating the breakthroughs needed to end our most devastating diseases."

    Dr. Wayne Koff, Ph.D., Founding CEO
    Dr. Wayne Koff, Ph.D., Founding CEO
    Human Immunome Project
  • "The immune system holds one of the most promising pathways to curing diseases that have long evaded treatment. Major initiatives are needed to turn that emerging science into real-world solutions faster — bringing us closer to therapies that save lives."

    Dr. Elaine Y. Hsiao, Ph.D.
    Dr. Elaine Y. Hsiao, Ph.D.
    Professor & Leading Immunology and Brain Health Researcher
  • "Blood Cancer United strongly supports Prop 38. This measure will strengthen California’s research and clinical trial infrastructure, helping patients access cutting-edge therapies sooner while accelerating the search for cures."

    Adam Zarrin, Director of State Gov. Affairs
    Blood Cancer United
  • "The Parkinson Association of Northern California supports Prop 38 because it drives disease-modifying research focused on slowing or stopping Parkinson’s, not just managing its symptoms. This work advances our understanding of the gut-immune-brain connection, where the disease may originate, and holds real potential to save lives.”

    Jan Whitney, Executive Director
    Parkinson Association of Northern California
  • "We stand at a threshold of exciting breakthroughs in treating intractable diseases. We need to support cure-finding research in immunology and immunotherapies."

    Dr. Steve A. Kay, Ph.D., D.Sc., FRS
    Dr. Steve A. Kay, Ph.D., D.Sc., FRS
    Professor and Director, University of Southern California; Member, National Academy of Sciences
  • "We believe California should lead the nation in science funding, and Prop 38 is a prime example of how strategic investment can improve the health outcomes of all Californians."

    Dr. Margaret Hitchcock, Ph.D., President
    California Colorectal Cancer Coalition
  • "Immunology research is our most powerful tool for preventing and curing diseases ranging from cancer to Alzheimer's. Prop 38 will accelerate lifesaving discoveries, strengthen our preparedness for future health threats and deliver hope to millions of families."

    Dr. Peter Hotez, M.D., Ph.D.
    Dr. Peter Hotez, M.D., Ph.D.
    Pediatrician and Vaccine Scientist
  • "Prop 38 is an important part of the equation to help close the gap in health outcomes for black Californians and other vulnerable communities."

    Rhonda Smith, Executive Director
    California Black Health Network
Titles and affiliations are for identification purposes only.

Frequently Asked Questions

Medical research funded by this measure will be conducted here in California at leading universities and medical research institutions that are well-qualified to conduct breakthrough immunology and immunotherapy research.

That may include University of California campuses, such as UCLA, UC Berkeley, UC San Diego, UC San Francisco, UC Irvine, UC Davis, and UC Riverside; private non-profit universities, such as Stanford, USC and Caltech; and non-profit research institutions such as City of Hope, Cedars-Sinai, and Sanford Burnham Prebys, among others.

Any cure or immunotherapy developed through research funded by Prop 38 must be made available to California patients at a 20% discount below the national average. That affordability protection is written directly into the measure — it’s not optional.

Yes. Prop 38 funding may only be awarded to California-based nonprofit universities and research institutions with demonstrated expertise in immunology and immunotherapy research.

Prop 38 is designed to fully pay for itself with no cost to the state or taxpayers. Ten percent (10%) of all proceeds from the licensing of immunotherapies must be returned to the State of California to offset the total cost of the bond measure, including interest. Furthermore, preventing and curing the most pressing diseases will reduce long-term healthcare expenses and save families and the state tens of billions of dollars in avoided medical expenses.

Prop 38 includes strong accountability and transparency requirements, including limiting state administrative costs to run the program to no more than 2%, requiring all grant funds to nonprofit universities and research centers be spent directly on medical research, rigorous conflict of interest rules, public disclosure of all spending and independent financial audits.

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